Research Initiative

Predictive Digital Phenotyping for Early Depression Detection in Young Adults

DeepVYBE combines digital phenotyping, conversational assessment, and Responsible AI to support earlier, ecologically valid, and clinically interpretable depression screening for young adults.

Digital phenotyping illustration with one chart

Why it matters

Relevance

Depression among young adults remains one of the most pressing mental health challenges, with substantial personal, social, and economic consequences. Current screening practices rely mainly on self-report and episodic clinical contact, which may fail to capture behavioural changes as they emerge in everyday life.

This project addresses that gap by combining digital phenotyping, conversational assessment, and Responsible AI to support earlier, more ecologically valid, and clinically interpretable depression screening workflows. Its relevance lies in its potential to support mental health services with non-invasive, scalable, and human-supervised screening tools.

Core Research Directions

Digital Phenotyping

Passive behavioural signals from smartphones and computers, combined with validated self-report and ecological momentary assessment.

Conversational Assessment

LLM-mediated conversational assessment integrated into screening workflows for more ecologically valid, interpretable signals.

Responsible AI & Oversight

Early risk signalling with transparent, privacy-aware models reviewed through psychologist-facing dashboards and clinical supervision.

Implementation

Pipeline

The project follows a structured workflow from clinical framing to pilot evaluation, integrating passive and active data collection with human-supervised AI outputs.

Step 1

Clinical screening framework

Definition of the clinical screening framework and identification of behavioural indicators associated with depression.

Step 2

Digital data collection

Development of infrastructure combining passive behavioural signals from smartphone and computer interaction, validated self-report measures, and LLM-mediated conversational assessment.

Step 3

Engagement layer

Exploration of a lightweight mobile interactive environment with gamified elements to support naturalistic assessment without shifting focus away from screening.

Step 4

Responsible AI & clinical review

Development of Responsible AI models for early risk signalling, with outputs reviewed through a psychologist-facing dashboard.

Step 5

Pilot evaluation

Iterative refinement and evaluation in pilot studies focusing on feasibility, acceptability, usability, and clinical relevance.

Consortium

Team

The consortium combines complementary expertise required to execute the project end-to-end, including clinical psychology, behavioural assessment, digital phenotyping, human-centered AI, and software development. This multidisciplinary composition is essential to ensure that the project is clinically grounded, technically robust, and feasible in real-world settings.

The team brings together expertise in depression assessment, conversational AI, behavioural data analysis, privacy-aware digital health systems, and mobile application development, supported by access to an institutional clinical context that strengthens feasibility and pilot validation capacity.

Meet the team